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Gender reassignment hormone therapy

The role of the endocrinologist is to introduce and monitor gender reassignment hormone therapy. Patients require diagnostic confirmation by an experienced psychologist or psychiatrist. The hormone system is then checked to document that there are no contraindications. In male-to-female transsexualism, gender reassignment hormone therapy is carried out with oestrogen tablets and blockage of the testosterone receptor with cyproterone acetate.

Only testosterone is administered in female-to-male transsexualism; antioestrogens are not necessary. The effects of gender reassignment hormone therapy are irreversible, and it has to be carried out for the rest of the patient’s life; this then prevents osteoporosis. Gender reassignment hormone therapy must be monitored by an endocrinologist for two years; only then can gender reassignment surgery be performed.

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