Microsomia is extremely burdensome for people affected by it. It is therefore all the more important to determine whether microsomia is present. Corresponding charts with percentiles are available for this. Many people are familiar with these from the examination booklets of infants. Microsomia is defined as a body size below the 10th percentile. However, it is more important whether a person crosses the percentiles, i.e. whether growth comes to a standstill.
Causes of growth disorders:
- Genetic defects
- Chronic diseases (e.g. anaemia, chronic renal insufficiency)
- Hormonal causes (e.g. too much cortisone in the blood, hypothyroidism or very frequently growth hormone deficiency or growth hormone or IGF-1 receptor defects)
- After chemotherapy radiotherapy
- With nutritional diseases
- Metabolism defects
In diagnosis, measuring the age of the bones is important; this can be seen and measured in an X-ray image of the left hand. A human, genetically engineered growth hormone that can be prescribed and managed by endocrinologists is available as therapy. On administration, such therapy leads to a normal body size. IGF-1 can now also be prescribed as therapy.